Trf2r
Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle. It is also known as TERF2, TRF2, and TRBF2, and is encoded in humans by the TERF2 gene. It is a component of the shelterin nucleoprotein complex and a second negative regulator of telomere length, playing a key role in … See more TERF2 has a similar structure to that of TERF1. Both proteins carry a C-terminus Myb motif and large TERF1-related dimerization domains near their N-terminus. However, both proteins exist exclusively as See more TERF2 is also known to recruit certain client proteins, also known as accessory factors. These client proteins are often recruited to TERF2 for a specific function at a specific time, … See more • Bilaud T, Koering CE, Binet-Brasselet E, Ancelin K, Pollice A, Gasser SM, Gilson E (April 1996). "The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human". Nucleic Acids Research. 24 (7): 1294–303. doi See more This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length, and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from … See more Cancer Telomerase is an enzyme that works to create telomeric ends for DNA, and it is thought to play … See more • PDBe-KB provides an overview of all the structure information available in the PDB for Human Telomeric repeat-binding factor 2 (TERF2) See more http://qcodes.github.io/Qcodes/examples/DataSet/Working-With-Pandas-and-XArray.ipynb
Trf2r
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