WebList of narrow therapeutic index drugs; Therapeutic index equation. The therapeutic index … WebZ Drugs with a high therapeutic index (e.g., divalproex, 50–125 mcg/ml) have a high margin of safety; that is, the therapeutic dose and the toxic dose are far apart. Z Drugs with a low therapeutic index (e.g., lithium, 0.5–1.2 mEQ/L) have a low margin of safety; that is, the therapeutic dose and the toxic dose are close together.
Therapeutic index - Wikipedia
WebThe recommended drug classes for therapeutic drug monitoring include: Antiarrhythmics, Antibiotics, Anti-cancer drugs, Antidepressants, Antiepileptics Antipsychotics, Bronchodilators, Cardiac drugs, HIV drugs, Immunosuppressant drugs and Lithium WebTHC and CBD Drug-Drug Interactions Med Cannabis Cannabinoids 5 DOI: … biologically sound and functional dentition
Narrow Therapeutic Index Drugs DrugBank Online
WebFollowing are some of the drugs that are commonly checked and the normal target levels: Acetaminophen: varies with use. Amikacin: 15 to 25 mcg/mL (25.62 to 42.70 micromol/L) Amitriptyline: 120 to 150 ng/mL (432.60 to 540.75 nmol/L) Carbamazepine: 5 to 12 mcg/mL (21.16 to 50.80 micromol/L) WebSome examples of drugs with a narrow therapeutic index are as follows: • Warfarin • Lithium • Digoxin • Phenytoin • Gentamicin • Amphoteracin B • 5-fluouracil • Zidovudine View chapter Purchase book Principles of Toxicology T.C. Vandivort, D.L. Eaton, in Reference Module in Biomedical Sciences, 2014 Therapeutic Index WebJan 1, 2024 · Based on impaired clearance, dosages should be decreased considerably, especially for drugs with a low therapeutic index. Hypothetically, high-clearance compounds are affected more than low ... biologically speaking a pigment: