Ddb1- and cul4-associated factor 8

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August undefined, 2024

WebDDB1 is a multidomain protein that interacts with Cul4A or Cul4B, the highly homologous Cul4 isoforms that serve as regulatory scaffolds for E3-RING ROC1 protein and E2 activities, acting as an adaptor to recruit specific targets for ubiquitination.73 Cul4-RING E3 ubiquitin ligases are classically involved in the control of DNA replication, cell … WebApr 14, 2024 · DDB1- and CUL4-associated factor 8 (DCAF8) is a WD40 repeat-containing protein, which serves as a substrate receptor for CRL4. The physiological role …

Entry - *615820 - DDB1- AND CUL4-ASSOCIATED FACTOR 8; DCAF8 …

WebSep 22, 2024 · DCAF8L2 DDB1 and CUL4 associated factor 8 like 2 [ (human)] Gene ID: 347442, updated on 22-Sep-2024 Summary Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2024] Other designations WebThe cullin 4 (CUL4)-damage-specific DNA binding protein 1 (DDB1)-cereblon (CRBN) E3 ubiquitin ligase co-exists in the same complex with and promotes the degradation of ClC-2 channels. fasting effects on cholesterol levels

Switching DCAFs: Beyond substrate receptors - PubMed

Webconditions.DDB1-andCUL4-associatedfactor8 (DCAF8)isaWD40repeat-containingprotein,whichservesasa substrate receptor for CRL4. The physiological role of … WebMar 21, 2024 · DCAF15 (DDB1 And CUL4 Associated Factor 15) is a Protein Coding gene. UniProtKB/Swiss-Prot Summary for DCAF15 Gene Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins (PubMed: 16949367 , … WebDec 4, 2024 · DCAF8 DDB1 and CUL4 associated factor 8 [ (human)] Gene ID: 50717, updated on 4-Dec-2024 Summary This gene encodes a WD repeat-containing protein … french louis style bedside table

DCAF15 Gene - GeneCards DCA15 Protein DCA15 Antibody

WebDDB1- AND CUL4-ASSOCIATED FACTOR 8; DCAF8 Alternative titles; symbols WD REPEAT-CONTAINING PROTEIN 42A; WDR42A HGNC Approved Gene Symbol: DCAF8 Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:160,215,720-160,262,549 (from NCBI) Gene-Phenotype Relationships PheneGene Graphics TEXT Description WebDescription: Homo sapiens denticleless E3 ubiquitin protein ligase homolog (Drosophila) (DTL), mRNA. Transcript (Including UTRs) Position: hg19 chr1:212,208,919 ... fasting effects on bodyWebDDB1 and CUL4 associated factor 15 is a protein that in humans is encoded by the DCAF15 gene. [5] DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin ligase activity and is responsible for the proteasome degradation of certain proteins. [6] References [ edit] french louisiana cities

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Ddb1- and cul4-associated factor 8

DCAF11 Gene - GeneCards DCA11 Protein DCA11 Antibody

WebThe cullin 4 (CUL4)-damage-specific DNA binding protein 1 (DDB1)-cereblon (CRBN) E3 ubiquitin ligase co-exists in the same complex with and promotes the degradation of ClC … WebMouse Gene Ddb1 (ENSMUST00000025649.9) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default) Description: Mus musculus damage …

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WebApr 10, 2024 · DDB1 and CUL4 associated factor 8 like 2. EIF4G1: Eukaryotic translation initiation factor 4 gamma 1. ERBB2: Erb-b2 receptor tyrosine kinase 2. PLXNB3: LRP1B, plexin B3. PNISR: PNN interacting serine and arginine rich protein. TRPC5: Transient receptor potential cation channel subfamily C member 5. WebSep 30, 2024 · The cullin-4-based RING-type (CRL4) family of E3 ubiquitin ligases functions together with dedicated substrate receptors. Out of the ˜29 CRL4 substrate receptors …

WebApr 5, 2024 · DTL是CUL4-DDB1相关因子（DDB1 and CUL4 associated factor，DCAF）之一，可能参与恶性肿瘤的发展过程 [2]。 Cullin-RING E3泛素连接酶（Cullin-RING E3 ligase，CRL）拥有庞大的家族，参与基因转录、细胞周期调控、细胞分化、增殖、凋亡和肿瘤发生等过程 [3]。 WebDDB1- and CUL4-associated factor 8-like protein 2 isoform X1: starting from $99.00: NM_008821.2: NP_032847.2: DDB1- and CUL4-associated factor 8-like protein 2: starting from $99.00: Learn more about the CRISPR gRNA constucts. Legal Statement of GenCRISPR Services and Products (Updated on July 28, 2015):

WebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) enhances the survival and maintenance of multipotent cells through promoting the Cullin 4 E3 ligase complex … WebDec 21, 2004 · DDB1- and CUL4-associated factor 8 Alternative names WD repeat-containing protein 42A Gene names Name DCAF8 Synonyms H326, WDR42A Organism …

WebMar 21, 2024 · DDB1 may recruit specific substrate targeting subunits to the DCX complex (PubMed:11673459, 12732143, 15882621, 18593899, 28886238). These substrate targeting subunits are generally known as DCAF (DDB1- and CUL4-associated factor) or CDW (CUL4-DDB1-associated WD40-repeat) proteins (PubMed:17079684, 16949367, …

WebDDB1- AND CUL4-ASSOCIATED FACTOR 13; DCAF13 Alternative titles; symbols WD REPEAT- AND SOF1 DOMAIN-CONTAINING PROTEIN 1; WDSOF1 HGNC Approved Gene Symbol: DCAF13 Cytogenetic location: 8q22.3 Genomic coordinates (GRCh38): 8:103,415,386-103,443,453 (from NCBI) TEXT Description french lounge chairWebIn affected members of a German family with autosomal dominant giant axonal neuropathy-2 (GAN2; 610100 ), originally reported by Vogel et al. (1985), Klein et al. (2014) identified … fasting effects on brainWebSep 30, 2024 · Out of the ˜29 CRL4 substrate receptors reported, the DDB1- and CUL4-associated factor 1 (DCAF1) is essential for cellular survival and growth, and its deregulation has been implicated in tumorigenesis. We carried out biochemical and structural studies to examine the structure and mechanism of the CRL4 DCAF1 ligase. fasting effects on liverWebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) is involved in DNA damage and repair [].Recently, DDB1 has been recognized as an adapter protein of Cullin 4A (Cul4A) E3 ligase complex [].CUL4-DDB1 E3 ligase (CRL4 DDB1) complex could target the downstream substrates for ubiquitination and subsequent degradation and then affect … french lounge sushiWebAug 31, 2024 · Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory … french louis xv armchairsWebDec 8, 2024 · Gene ID: 320808, updated on 8-Dec-2024 Summary Located in mitochondrion. Orthologous to human DCAF5 (DDB1 and CUL4 associated factor 5). [provided by Alliance of Genome Resources, Apr 2024] Other designations DDB1- and CUL4-associated factor 5, WD repeat domain 22, WD repeat-containing protein 22 french lounge musicWebJun 22, 2007 · The CUL4-DDB1 ubiquitin ligase regulates cell proliferation, survival, DNA repair, and genomic integrity through targeted ubiquitination of key regulators, yet the substrate receptors that dictate the specificity of this ubiquitination machinery have been largely unknown. french lounge